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January 2019

20190111
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Neuron Cofund

Date: 11.01.2019 - 11.03.2019
Neuron Cofund

Multinational Research Projects on Translational Biomarkers in Brain Disorders

Announcing Institution:

National Centre for Science and Development

Scope of the call:

Research proposals should cover at least one of the following areas:

 

a) Fundamental research addressing the discovery and validation of biomarkers to be used as bio signatures of the pathophysiology associated to specific neurological and psychiatric diseases.
b) Clinical research on clinically relevant biomarkers for the diagnosis, patient stratification, prognosis or monitoring or prediction of treatment response and side effects for specific neurological and psychiatric diseases.

Call supervisor at CAWP:

Agnieszka Kołodziejska-Skrobek
phone: 12 663 30 23,
e‑mail: agnieszka.kolodziejska-skrobek@uj.edu.pl

Proposals may include hypothesis-driven studies on a variety of biomarkers, e.g. structural, functional, molecular, genetic biomarkers. Digital, behavioral or cognitive biomarkers are eligible only in combination with other bio signatures. In all cases, a clear pathophysiological correlate and studies on human participants or tissue should be included in the proposal. Clinical studies are eligible up to the point of proof of concept1. 

To address an important translational gap in the biomarker validation process, proposals are encouraged to perform retrospective validation for pre-identified candidates using high quality data samples such as highly stratified patients populations and rigorous analytical methods. Moreover, the combination of at least two types of biomarkers is required for biomarkers’ validation studies.

Submission of the proposals:

Pre-proposals must be submitted in electronic format via the electronic submission system.

Deadline:

11th March 2019 14.00 CET

More information:

Call text

Country-specific information

Pre-proposal application form